
AESTHETIC & REGENERATIVE MEDICINE
Polynucleotides
Advanced regenerative injectables designed to improve skin quality at a cellular level.
Book ConsultationAbout Polynucleotides
Polynucleotides are advanced regenerative injectables designed to improve skin quality at a cellular level. Derived from DNA fragments, they stimulate tissue repair, collagen production, and deep hydration, helping to improve skin texture, elasticity, and overall skin health.
Ideal for delicate or compromised skin, they are particularly effective for fine lines, wrinkles, acne scars, and skin aging. They are particularly effective for under-eye rejuvenation, face, neck, and décolletage, delivering natural, long-lasting rejuvenation with minimal downtime.

HOW IT WORKS
Cellular Regeneration
Polynucleotides work at a cellular level to stimulate your skin's natural repair mechanisms. Derived from DNA fragments, they promote tissue regeneration, enhance collagen synthesis, and improve overall skin health.
This makes them particularly effective for treating delicate areas like the under-eyes, where traditional fillers may not be suitable.
- Stimulates tissue repair at cellular level
- Boosts collagen and elastin production
- Deep hydration from within
- Ideal for delicate and compromised skin

IDEAL FOR
Who Should Consider This Treatment?
Polynucleotides are an excellent choice for patients seeking natural skin regeneration without the use of traditional fillers. They are particularly suitable for those with:
- Fine lines and wrinkles
- Acne scars and skin damage
- Dull, dehydrated skin
- Loss of skin elasticity
WATCH
See Polynucleotides in Action
Watch our reel to see how this regenerative treatment works and the results you can expect.
Video coming soon
Frequently Asked Questions
Everything you need to know about polynucleotide treatments.
Polynucleotides are DNA fragments derived from salmon or trout that stimulate tissue repair and collagen production when injected into the skin.
A course of 2-3 treatments spaced 3-4 weeks apart is typically recommended for optimal results.
Minimal downtime is expected. Some swelling or redness may occur but typically resolves within 72 hours.
Results develop gradually over 4-8 weeks as collagen production increases. Full results are typically visible after completing the recommended course.
Dr Nabil Jetha, MBBS, BSc (Hons), PGDip (Aesthetics), GMC 7751313, practises aesthetic and skin medicine at 120 Pall Mall, St James’s, central London.
His background is in medicine first and aesthetics second, and his practice is built around assessment rather than treatment menus: working out what is actually driving a concern before deciding whether anything needs doing about it.
Every article on this site is written and medically reviewed by Dr Nabil. Consultations are prescriber-led, which means the doctor assessing you is the same person responsible for anything prescribed, rather than a prescriber signing remotely for someone else.
His registration can be checked by anyone on the GMC medical register using reference number 7751313.
